These include:. Be aware that while selective beta-blockers are not as likely to cause pulmonary side effects as non-selective beta-blockers, they can cause pulmonary side effects, especially at high doses. When taking these drugs, you may experience shortness of breath, wheezing, asthma or COPD exacerbation, or more subtle respiratory effects that can be measured with diagnostic tests. Cardioselective beta-blockers may reduce forced expiratory volume FEV1. This is more common when you first start taking them.
FEV1 is a measure of the volume of air that you can expire with maximal effort in one second. In most cases, the FEV1 will normalize within a week or two once your body adapts to the drug. While cardioselective beta-blockers are available, your medical team will work with you to tailor your treatment to your specific needs—and you may need a prescription for a non-cardioselective beta-blocker.
Keep in mind that people react differently to different drugs, so it is important that you watch for any new respiratory symptoms, such as changes in your breathing pattern or any increases in the severity or frequency of your exacerbations. Looking to start a diet to better manage your high blood pressure?
Our nutrition guide can help. Ann Pharmacother. American Heart Association. Cardiac Medications. Updated July 31, Med Arch. Respiratory effects of beta-blocker therapy in heart failure. Cardiovasc Drugs Ther. Drugs should be started at a low dosage and titrated upward. Care is necessary in patients with severe asthma or ongoing bronchospasms.
Already a member or subscriber? Log in. Interested in AAFP membership? Learn more. Salpeter SR, et al. Ann Intern Med. November 5, ;—7. This content is owned by the AAFP. Reddel, H. Care Med. Decalmer, P. Beta-blockers and asthma. Heart J. Schoene, R. Timolol-induced bronchospasm in asthmatic bronchitis. Zimmerman, T. Topical ophthalmic beta blockers: A comparative review. Short, P. Randomized placebo-controlled trial to evaluate chronic dosing effects of propranolol in asthma.
Sheppard, D. Effects of esmolol on airway function in patients with asthma. Barnett, M. Badgett, R. Variations in pharmacology of beta-blockers may contribute to heterogeneous results in trials of perioperative beta-blockade. Anesthesiology , — Baker, J. The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
California; SIGN Edinburgh; National Asthma Education and Prevention Program. Expert panel report 3 EPR-3 : Guidelines for the diagnosis and management of asthma-summary report Allergy Clin. Melbourne; Ichinose, M. Japanese guidelines for adult asthma Pujet, J.
Effects of celiprolol, a cardioselective beta-blocker, on respiratory function in asthmatic patients. Schindl, R. The effect of the cardioselective beta blocker celiprolol on pulmonary function in asthmatic patients. Lainscak, M. Differences between bisoprolol and carvedilol in patients with chronic heart failure and chronic obstructive pulmonary disease: a randomized trial. Download references. This paper presents independent research. The views expressed in this publication are those of the authors and not necessarily those of the acknowledged institutions.
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Abstract Beta-adrenergic blocking agents abbreviated as beta-blockers have been used for treating various cardiovascular diseases. Introduction Beta-adrenergic blocking agents or beta-blockers have been frequently used to treat various cardiovascular disorders such as hypertension, ischemic heart disease, cardiac arrhythmias, and congestive heart failure 1 , 2 , 3 , 4.
Methods The detailed description of method is listed in eTable 1. Results After the initial screening procedure, a total of articles were considered for full-text review Fig. Scand J Respir Dis — Johnsson G, Svedmyr N, Thiringer G Effects of intravenous propranolol and metoprolol and their interaction with isoprenaline on pulmonary function, heart rate and blood pressure in asthmatics. Eur J Clin Pharmacol 6: — Article Google Scholar.
Br Med J — Download references. Clatterbridge Hospital, Bebington, Merseyside, England. Sahay, S. You can also search for this author in PubMed Google Scholar. Reprints and Permissions.
Lawrence, D. Asthma and beta-blockers. Eur J Clin Pharmacol 22, — Download citation. Received : 21 May
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